Lock var þekktur fyrir þátttöku sína í breskum pallborðsþáttum, bæði á BBC og Channel 4, þeirra á meðal 8 Out of 10 Cats þar sem hann gegndi hlutverki liðsstjóra.
Í frétt BBC segir að hann hafi einnig verið reglulegur gestur í þáttunum QI, The Last Leg, Have I Got News for You og The Big Fat Quiz of the Year.
Lock fæddist í Surrey og hætti í skóla snemma á níunda áratugnum og hóf þá störf sem iðnaðarmaður. Hann fékk á þeim árum húðkrabbamein en jafnaði sig að fullu og fór þá að einblína á feril sinn sem grínisti í sjónvarpi.
Lock gegndi hlutverki liðsstjóra í 8 Out of 10 Cats fyrstu átján þáttaraðirnar, þar sem hann keppti bæði á móti þeim Jason Manford og Jon Richardson auk gesta. Jimmy Carr hefur verið stjórnandi þáttanna. Lock hætti í þáttunum árið 2015 og tók Rob Beckett þá við stöðunni.
Fjölmargir hafa minnst Lock, þeirra á meðal samstarfsmenn hans í sjónvarpi.
Brutal news about Sean Lock today.
— Jimmy Carr (@jimmycarr) August 18, 2021
I loved him. I m watching clips of him right now - laughing & crying. I ll miss him so much.
Such sad news. RIP the great Sean Lock. One of the funniest, most influential comedians of a generation. A lovely man.
— Ricky Gervais (@rickygervais) August 18, 2021
Over 15 years producing '8 Out Of 10 Cats' Sean Lock made me laugh so much and so often. A unique and brilliant comic voice. Love to his family and his many friends #RIPSean
— Richard Osman (@richardosman) August 18, 2021
Incredibly sad to learn of the loss of one of our greatest comedians, Sean Lock. A much loved part of the C4 family he s played a huge role on the channel for over 2 decades, and we ll miss him. Our thoughts are with his family and friends pic.twitter.com/HrT6mjZLjT
— Channel 4 (@Channel4) August 18, 2021
Sean Lock was a brilliant comedian and I always learned something watching him work. Thoughts with his friends and family. Very shocking and sad. RIP.
— Katy Brand (@KatyFBrand) August 18, 2021
It s heartbreaking to lose my dearest friend Sean Lock , he was a true original, a wonderful comic. All my thoughts are with his family.
— Bill Bailey (@BillBailey) August 18, 2021
So sorry to hear this. Farewell Sean, you brought a wonderful comedic talent to the world and you will be missed -
— Eddie Izzard (@eddieizzard) August 18, 2021
Sean Lock: Comedian and 8 Out Of 10 Cats panellist dies from cancer aged 58https://t.co/up38yGeYKq pic.twitter.com/7IF7S5W6H9
Awful news. Such a funny man. #RIPSean https://t.co/8GM87iowOD
— Gary Lineker (@GaryLineker) August 18, 2021
Sad news about Sean Lock. Funny on stage, hilarious off. We met in 1988 right at the start of our stand up careers. I hadn t seen him in recent years as he quietly wrestled with illness but I feel very sad today for Anoushka and their children. RIP Locky.
— Alan Davies (@alandavies1) August 18, 2021
I wish I had the words to describe the exceptional man that was Sean Lock. But today I don t, and I think he might have liked it that way.
— Susie Dent (@susie_dent) August 18, 2021